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KMID : 0359920080270010133
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Korean Journal of Nephrology
2008 Volume.27 No. 1 p.133 ~ p.136
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A Case of Primary Amyloidosis with Nephrotic Syndrome and Factor X Deficiency
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Kim Min-Young
Kwak Soo-Young
Kim Kyung-Hee
Lee Ji-In
Ha Young-Eun
Kim Dae-Joong
Oh Ha-Young
Lee Jung-Eun
Huh Woo-Sung
Kim Yoon-Goo
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Abstract
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We report a case of nephrotic syndrome and factor X deficiency secondary to primary amyloidosis. A 58-year-old man was referred to our hospital for evaluation of nephrotic syndrome and bleeding tendency.
He was confirmed to have primary amyloidosis by renal biopsy, immunofixation electrophoresis and bone marrow findings. His bleeding tendency was due to prothrombin time prolongation caused by isolated factor X deficiency. If any patient with nephrotic syndrome has bleeding tendency due to coagulation abnormalities, that patient should be considered to have factor X deficiency secondary to primary amyloidosis.
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KEYWORD
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Factor X deficiency, Nephrotic syndrome, Amyloidosis
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